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BRM

Batch Record Management

Right-first-time electronic batch records

Design master batch records, execute them electronically on the shop floor, and review by exception. Every entry is attributable, contemporaneous, and permanently recorded.

21 CFR Part 11 EU Annex 11 ALCOA+ EU GMP Chapter 4

Overview

Why batch record management matters

Paper batch records are where data-integrity risk concentrates: missing entries, out-of-sequence steps, illegible corrections, and review cycles that hold finished product in quarantine for weeks. Zixov Batch Record Management moves the batch record itself into the system — designed once as a master template, executed electronically on the shop floor, and reviewed by exception.

Master batch records are built with enforced activity sequencing, in-process checks, calculations, and dual-verification points. During execution, operators can only complete steps in the permitted order, entries are validated as they're made, and any excursion is flagged and captured as a deviation in real time — not discovered at review three weeks later.

Because clean steps are verified at the point of execution, QA review focuses only on the exceptions. Combined with full batch genealogy and ALCOA+-compliant data capture, that turns batch release from a document-checking exercise into a decision.

80%

reduction in batch review time

50%

fewer documentation errors per batch

100%

attributable, contemporaneous entries

Typical outcomes reported by teams moving from paper and spreadsheet-based processes to Zixov.

See it in action

Batch Record Management inside Zixov

A look at the actual screens your team will work in — pick a view or let the tour play through.

app.zixov.com/batches/B-26-0713

Paracetamol 500mg — B-26-0713

MBR-PCM-500 v3 · Line 2

Dispensing

Granulation

Compression

Coating

Packing

Step 14.2

Compression force check

Entry

12.4 kN (limit 10–14)

Verified by

Dual sign — K. Patel / R. Das

Exceptions

1 flagged (step 9.4)

Yield to date

99.2%

Started

13 Jul, 06:12

Step 9.4 sieve integrity — deviation DEV-2026-0192 raised in-line.

Electronic execution with enforced step order — operators can only do the next right thing.

Challenges we solve

The problems this module was built to fix

Batch review bottlenecks release

Reviewing every line of a paper record delays release by days or weeks. Review-by-exception surfaces only flagged entries, cutting review effort dramatically.

Data-integrity gaps on the floor

Late entries, missing initials, and correction fluid are audit magnets. Electronic execution enforces contemporaneous, attributable entries with validated values.

Deviations discovered too late

On paper, excursions surface during review — long after the batch moved on. In-line capture raises the deviation the moment it happens, while evidence is fresh.

No usable batch genealogy

Tracing materials and equipment across batches from paper is near impossible. Electronic records give full forward and backward traceability in seconds.

Capabilities in depth

What BRM does, in detail

01

Master batch record design

Build MBR templates with activity sequencing, parameters, calculations, and verification points — version-controlled and approved like any controlled document.

  • Drag-and-drop activity and phase sequencing
  • In-process checks with limits and auto-calculations
  • Versioned, approved templates under change control
02

Electronic execution

Operators execute batches on the shop floor with enforced step order, validated entries, and dual verification where your process requires it.

  • Enforced step sequencing with conditional branching
  • Real-time entry validation against specifications
  • Dual verification and witness sign-offs at critical steps
03

Exception management

Out-of-limit entries, skipped checks, and process excursions are flagged immediately and routed into Deviation Management with full batch context attached.

  • Automatic exception flagging during execution
  • One-click deviation creation with batch context
  • Exception dashboard for in-progress batches
04

Review-by-exception & release

QA reviews only flagged entries against the full record, with batch genealogy and audit trail available inline — accelerating disposition decisions.

  • Exception-focused review workspace
  • Full batch genealogy and material traceability
  • Release sign-off with complete ALCOA+ audit trail

How it works

The batch record management lifecycle in Zixov

1

Design

Author the master batch record with sequenced activities, checks, and verification points; approve it under change control.

2

Issue

Instantiate an executable batch record for a specific batch, locked to the approved MBR version.

3

Execute

Operators work through enforced steps with validated entries; exceptions flag deviations in real time.

4

Review

QA reviews by exception, with every flagged entry linked to its investigation and resolution.

5

Release

Disposition the batch with e-sign-off, backed by complete genealogy and audit trail.

At a glance

Everything included

Master batch record templates with activity sequencing

Electronic batch execution with enforced step order

In-process checks, dual verification, and deviations capture

Review-by-exception to accelerate batch release

Batch genealogy and full traceability

ALCOA+ compliant data capture with audit logging

FAQ

Common questions about batch record management

How long does it take to digitize our batch records?

Most teams start with one product line. A typical MBR is templated, reviewed, and approved within days once the paper master is finalized — and subsequent products reuse common phases and checks.

Can operators use tablets on the shop floor?

Yes. Execution runs in a browser on tablets and workstations, with large-format entry screens designed for gowned operation.

What happens if a value is out of limits?

The entry is flagged immediately, the operator is prompted per your configured response (block, warn, or require verification), and a deviation can be raised in one click with the batch step context attached automatically.

Does it integrate with our equipment or LIMS?

The module is designed API-first, so balance readings, environmental data, and LIMS results can be brought into batch steps as your integration roadmap matures. Talk to us about your instrument landscape.

Better together

Works together with

Batch Record Management is one part of a connected quality suite — records flow between modules automatically, so nothing is re-entered and nothing falls through.

See Batch Record Management in a live demo

30 minutes, tailored to your workflows — bring one of your own processes and watch it run in Zixov.